Table 3.
Independent variable | Univariable | Multivariable | ||
---|---|---|---|---|
OR (95% CI), unadjusted | P value | OR (95% CI), adjusted | P value | |
Dementia | 6.84 (3.86–12.11) | <0.001a | 3.13 (1.71–5.70) | <0.001a |
Mean akinetic‐rigid score | 3.15 (2.14–4.64) | <0.001a | 2.38 (1.48–3.83) | <0.001a |
Immediate‐release l‐dopa‐carbidopa LEDD, mg/d | 1.17 (1.10–1.23) | <0.001a | 1.16 (1.08–1.26) | <0.001a |
Anticholinergic medication usage | 2.25 (1.204.24) | 0.012c | 2.83 (1.43–5.59) | 0.003b |
Controlled‐release l‐dopa‐carbidopa LEDD, mg/d | 1.02 (0.95–1.10) | 0.530 | 1.09 (1.00–1.19) | 0.040c |
Disease duration, y | 1.13 (1.07–1.18) | <0.001a | 1.04 (0.99–1.10) | 0.140 |
Dopamine agonist LEDD, mg/d | 0.73 (0.60–0.89) | 0.002b | 0.86 (0.71–1.04) | 0.110 |
Mean tremor score | 1.30 (0.86–1.95) | 0.210 | 0.67 (0.40–1.11) | 0.121 |
Depression | 1.96 (1.18–3.26) | 0.009b | 1.50 (0.81–2.78) | 0.198 |
Abbreviations: OR, odds ratio; CI, confidence interval; LEDD, l‐dopa equivalent daily dosage; All LEDD variables were divided by 100 to facilitate OR interpretation.
P < 0.001.
P < 0.01.
P < 0.05.