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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Br J Haematol. 2018 Jan 24;180(4):571–577. doi: 10.1111/bjh.15076

Table II.

Final multivariable model of prospective rate of ACS in Children with SCAa (N= 163)

Covariate IRR 95% CI P value
Male gender 0.70 0.46–1.05 0.080
History of wheezing leading to shortness of breath 1.95 1.22–3.13 0.006
History of an ACS episode prior to 4 year of age 2.41 1.62–3.59 <0.001
Number of positive aeroallergen skin tests 1.23 1.11–1.36 <0.001

Abbreviations: ACS=acute chest syndrome; SCA=sickle cell anemia; IRR=incidence rate ratio; CI=confidence interval

a

Negative binomial regression models with adjustment for over-dispersion, using robust standard errors. Two-tailed significance values.