Table 2.
Proportion of amygdala enlargement (AE) across different types of nonlesional epilepsy
| LRE | IGE | HC | FE value | p-value | |
|---|---|---|---|---|---|
| Left AE | 16/136 (11.8%) | 2/34 (5.9%) | 10/233 (4.3%) | 7.05 | 0.003 |
| Right AE | 19/136 (14.0%) | 1/34 (2.9%) | 7/233(3.0%) | 15.53 | 0.00038 |
| Total AE | 25/136 (18.4%) | 2/34 (5.9%) | 15/233 (6.4%) | 12.72 | 0.001 |
| Unilateral Temporal | Unilateral Extratemporal | χ2 | FE p-value | |
|---|---|---|---|---|
|
|
||||
| Ipsilateral AE* | 18/93 (19.4%) | 4/38 (10.5 %) | 1.51 | 0.305 |
| Contralateral AE* | 9/93 (9.7%) | 4/38 (10.5%) | 0.02 | 1.00 |
| Temporal z-scores | Extratemporal z-scores | Mann-Whitney U | ||||
|---|---|---|---|---|---|---|
|
|
||||||
| Range | Mean (SD) | Range | Mean (SD) | U | p-value | |
|
|
||||||
| Ipsilateral AE | 2.09 – 6.44 | 2.97 (1.11) | 2 – 4.47 | 3.19 (1.09) | 33 | 0.798 |
| Contralateral AE | 2.12 – 4.15 | 3.02 (0.7) | 2.47 – 3.26 | 2.83 (0.41) | ||
*
Ipsilateral and contralateral AE counts include cases with bilateral AE; therefore, single cases may be represented in both the ipsilateral and contralateral rows.
AE = amygdala enlargement, LRE = localization-related epilepsy, IGE = idiopathic generalized epilepsy, HC = healthy control, FE= Fisher’s Exact