Table 1.

Demographics of participants by study group (n=192).

Demographics	ES w/PDR (n=40)	ES no PDR (n=67)	No ES (n=85)	p-value
Female	73%	66%	84%	0.038
Married	90%	88%	83%	0.530
Age
Mean ± SD (range)	50 ± 13.6 (33–79)	50 ± 14.6 (22–84)	48 ± 14.2 (23–88)	0.600
Ethnicity and Race
White, Non-Hispanic	80%	88%	81%	0.431
Education
Up to HS or vocational training	8%	11%	16%	0.740
Some college/Associate degree	15%	22%	19%
College degree	33%	27%	26%
Advanced degree	45%	40%	39%
Employment
Employed (full or part-time)	68%	67%	59%	0.480
Current Religion (n=191)
Christian	58%	47%	41%	0.473
Jewish	20%	26%	38%
Other (Buddhist, Taoist, Meditation) or >1 religion	5%	6%	5%
None	18%	21%	16%
Parent study type
Breast cancer	28%	30%	36%	0.011
CHD	45%	49%	24%
CDH, DD, D, MCA, MW, ES	28%	21%	40%
Disease status (n=184)
Personally affected	33%	43%	46%	0.404
Children (n=191)
Affected children	70%	58%	50%	0.143
Unaffected children only	30%	34%	39%
No children	0%	8%	11%

Abbreviations: congenital heart disease (CHD), congenital diaphragmatic hernia (CDH), developmental delay (DD), diabetes (D), multiple congenital anomalies (MCA), muscle weakness (MW), exome sequencing study (ES), personal disease risk (PDR).

p-values were calculated by Chi-squared test or ANOVA (age variable)