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The AFD sensory neurons are activated by warming and inhibited by cooling. A) Idealized calcium transients (green) evoked by thermal up-steps (top) and down-steps (bottom) [35,17]. B) Idealized calcium transients (green) and thermoreceptor currents (violet) evoked by a rising thermal ramp [67]. Arrows indicate T*AFD C) Acclimation to a new Tc shifts T*AFD. Calcium transients are shown in green. Black traces in A–C show thermal stimuli delivered to immobilized animals.
