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Oxygen consumption and blood hormones in response to leptin infusion (2 μg/kg/min, iv) for 7 days). (A) Oxygen consumption (VO2), (B) changes in VO2 in response to leptin compared to baseline, (C) blood glucose, (D) insulin, and (E) leptin levels in male and female SOCS3flox/flox and SOCS3-Nestin-Cre mice. *p<0.05 compared to SOCS3flox/flox mice. #p<0.05 compared to baseline.
