Figure 5.
Body weight, fat and lean mass, and liver lipid analysis in male (n=6) and female (n=6) SOCS3flox/flox mice and male (n=6) and female (n=6) SOCS3-Nestin-Cre mice fed a HFFD. Liver fat and lean mass were assessed using EchoMRI. (A) Body weight, (B) body fat, (C) body lean mass, (D) SOCS3flox/flox and SOCS3-Nestin-Cre mice liver sections stained for Oil Red O and visualized at 20X magnification and liver weight and lean and fat mass, (E) food intake and body weight and (F) blood glucose concentration measured over 120 minutes post gavage during an oral glucose tolerance test (GTT), and blood glucose area under the GTT curve (AUC) for male and female SOCS3flox/flox and SOCS3-Nestin-Cre mice fed a HFFD.*p<0.05 compared to SOCS3flox/flox mice.
