. Author manuscript; available in PMC: 2019 Jun 1.

Published in final edited form as: Pediatr Nephrol. 2018 Mar 6;33(6):1069–1077. doi: 10.1007/s00467-018-3888-4

Table 4.

Urinary Biomarkers and CKD at Five-Year Follow-up Visit

	CKD (N=18)	No CKD (N=89)	P value
IL-18 Year 5 (pg/mL)	14.4 (7.3, 19.8)	15.1 (8.7, 23.9)	0.35
IL-18 Elevated at Year 5	0 (0%)	4 (4%)	0.36
IL18 (Change from pre-op) (pg/mL)	-4.6 (-8.8, 2.4)	-0.6 (-22.1, 12.9)	0.50
KIM-1 Year 5 (ng/mL)	0.3 (0.2, 0.6)	0.6 (0.3, 1.0)	0.04
KIM-1 Elevated at Year 5	2 (11%)	14 (16%)	0.62
NGAL Year 5 (ng/mL)	3.5 (1.6, 12.8)	4.7 (2.3, 9.3)	0.67
NGAL Elevated at Year 5	2 (11%)	1 (1%)	0.02
NGAL (Change from pre-op) (ng/mL)	-0.08 (-3.4, 2.1)	1.5 (-2.5, 5.0)	0.43
MCP1 MSD Year 5 (pg/mL)	85.9 (29.8, 176.2)	103.4 (47.4, 163.2)	0.56
YKL-40 MSD Year 5 (pg/mL)	223.5 (157.1, 442.0)	379.9 (151.4, 639.4)	0.31

Values are expressed as median [interquartile range] or Number (%). IL-18, interleukin-18; KIM-1, kidney injury molecule-1; MCP-1, monocyte chemoattractant protein-1: NGAL, neutrophil gelatinase–associated lipocalin; CKD, chronic kidney disease. Change from pre-op signifies the difference between the five-year biomarker level and the preoperative biomarker level