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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: Chromosoma. 2018 Jan 10;127(2):175–186. doi: 10.1007/s00412-018-0659-8

Figure 2. Ki-67 localization throughout the cell cycle.

Figure 2

HeLa S3 cells were stained with anti-Ki67 antibodies (green) and DAPI to visualize DNA (blue), illustrating different Ki-67 localizations across the cell cycle. In mitotic cells, Ki-67 coats the condensed chromosomes as the foundation of the perichromosomal layer. As cells exit mitosis and enter early G1 phase, small puncta of Ki-67 leave the decondensing chromosomes. These then coalesce at the periphery of the reformed nucleoli as G1 phase progresses. Scale bar, 10 μm.

This figure is reprinted from Matheson and Kaufman, Mol. Biol. Cell (2017), with permissions from the authors.