Table 4.
Multivariable Cox proportional hazards analysis for 12-month survival in liver transplant waitlist registrants with hepatitis C (HCV) or liver disease other than HCV.
| HCV | Non-HCV | |
|---|---|---|
| HR (95% CI) | HR (95% CI) | |
| Total population | N=7,627 | N=13,748 |
| Cohort 1 | 1.05 (0.88–1.24) | 1.13 (0.99–1.30) |
| Cohort 2 | 1.00 | 1.00 |
| Cohort 3 | 0.79 (0.67–0.93) | 0.97 (0.86–1.09) |
| Age | 1.03 (1.02–1.04) | 1.04 (1.03–1.05) |
| Lab-MELD score | 1.18 (1.16–1.19) | 1.15 (1.14–1.16) |
|
| ||
| Baseline MELD below 20 | N=6,779 | N=12,070 |
| Cohort 1 | 1.09 (0.90–1.31) | 1.15 (0.99–1.35) |
| Cohort 2 | 1.00 | 1.00 |
| Cohort 3 | 0.88 (0.73–1.06) | 0.97 (0.84–1.12) |
| Age | 1.03 (1.02–1.05) | 1.04 (1.03–1.04) |
| Lab-MELD score | 1.21 (1.18–1.24) | 1.17 (1.15–1.19) |
|
| ||
| Baseline MELD above 20 | N=848 | N=1,678 |
| Cohort 1 | 0.94 (0.65–1.35) | 1.05 (0.79–1.39) |
| Cohort 2 | 1.00 | 1.00 |
| Cohort 3 | 0.59 (0.42–0.82) | 0.82 (0.65–1.02) |
| Age | 1.02 (1.00–1.04) | 1.05 (1.04–1.06) |
| Lab-MELD score | 1.15 (1.13–1.18) | 1.10 (1.09–1.12) |
Abbreviations: HR, hazard ratio; CI, confidence interval; MELD, Model for End-stage Liver Disease