Figure 4.
A–C: The expression of mRNA for the mast cell protease MCP1 (A), and the mucin genes MUC5AC (B) and MUC5B (C) in the lung tissue. The expression of mRNA was measured by real-time PCR and the data expressed in reference to the expression level of 18S ribosomal RNA. D: A representative image of toluidine positive intraepithelial mast cells in the lung from a ST2 KO mouse with chronic experimental asthma. E: Comparison of intraepithelial mast cells between allergen-treated WT and ST2 KO mice. The results were shown as the number of mast cells per mm of basement membrane (BM).
