TABLE 3.

Results of Cox Regression Analyses of LV Function and Shape Indices From 2DE and 3DE Images: Risk Assessment of Long-Term CV Mortality in Patients Referred for Echocardiographic Examination

Cox Regression: CV Mortality (N = 416)
Unadjusted				Adjusted
	p Value	HR	95% CI	2D EF Model 1,140.9* 0.628 ± 0.32 (0.565–0.691)†			2D GLS Model 1,134.0* 0.676 ± 0.28 (0.620–0.731)†			3D EF Model 1,133.1* 0.658 ± 0.31 (0.597–0.719)†			3D GLS Model 1,124.2* 0.690 ± 0.29 (0.633–0.747)†
				p Value	HR	95% CI	p Value	HR	95% CI	p Value	HR	95% CI	p Value	HR	95% CI
Age	<0.01	1.036	1.02–1.05	<0.01	1.032	1.02–1.05	<0.01	1.028	1.02–1.04	<0.01	1.033	1.02–1.05	<0.01	1.032	1.02–1.05
BSA	0.031	0.474	0.24–0.93	0.031	0.431	0.20–0.93	0.021	0.406	0.19–0.87	0.063	0.508	0.25–1.04	0.033	0.462	0.23–0.94
Sphericity	0.113	11.6	0.56–242	0.063	0.000	0.00–1.76	0.201	0.001	0.00–47.4	0.069	0.000	0.00–2.19	0.105	0.000	0.00–6.46
Conicity	0.031	0.002	0.00–0.58	0.208	0.000	0.00–1.5K	0.332 0.000		0.00–36K	0.385	0.000	0.00–100K	0.284	0.000	0.00–9.3K
Anterior	0.661	1.415	0.30–6.67	0.875	1.168	0.17–8.10	0.916	0.899	0.12–6.51	0.933	1.086	0.16–7.47	0.964	0.956	0.14–6.63
Septum	0.151	0.351	0.08–1.47	0.262	0.328	0.05–2.30	0.427	0.465	0.07–3.07	0.234	0.312	0.05–2.13	0.270	0.338	0.05–2.32
Inferior	0.027	4.835	1.20–19.5	0.058	4.959	0.95–25.9	0.109	3.827	0.74–19.8	0.039	5.47	1.09–27.4	0.045	4.939	1.03–23.6
Lateral	0.646	2.240	0.07–70.3	0.123	27.70	0.41–1.9K	0.820	1.655	0.02–126	.240	12.48	0.19–838	0.383	6.47	0.10–431
2D EF	<0.01	0.975	0.96–0.99	<0.01	0.963	0.95–0.98
2D GLS	<0.01	1.123	1.08–1.17				<0.01	1.140	1.09–1.19
3D EF	<0.01	0.973	0.96–0.98							<0.01	0.961	0.95–0.97
3D GLS	<0.01	1.091	1.06–1.12										<0.01	1.113	1.08–1.15

^*−2LL AUC.

^†AUC ROC – SE (95% CI). Bold indicates p < 0.05.

−2LL = −2 logarithmic likelihood; AUC ROC = area under curve in receiver-operating characteristic analysis; BSA = body surface area; CI = confidence interval; HR = hazard ratio.