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. 2018 Apr 17;9(29):20747–20760. doi: 10.18632/oncotarget.25087

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Copyright: © 2018 Weidenbusch et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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(A) Overall survival (OS) using the Kaplan-Meier estimator between patients receiving targeted therapy (TT=9) and those who did not (non TT=11). Median OS=8.83 months in the TT group versus 4.93 months in the non TT group. Log-rank P=0.0014, Gehan-Breslow-Wilcoxon P=0.0025, with a hazard ratio (HR) of 0.1435 and a 95% confidence interval (CI) ranging from 0.044 to 0.471. (B) Progression free survival (PFS) using the Kaplan-Meier estimator between patients receiving targeted therapy (TT=9) and those who did not (non TT=10 patients since PFS was not available for PT18). Median PFS=6.17 months in the TT group versus 1.6 months non TT group. Log-rank test (P=0.0011) and the Gehan-Breslow-Wilcoxon test (P=0.0015) with a HR of 0.1448, 95% CI of 0.045 to 0.463.