Table 4. DEmiRNAs found in the discovery phase for MIBC analysed in the TCGA dataset.
| ID miRNA (present study) | ID miRNA (TCGA) | Mean read counts | log2 Fold Change | adj P (Bonferroni) | adj P (FDR) |
|---|---|---|---|---|---|
| miR-30a-5p | miR-30a | 179888 | –2.496 | 5.28045E–21 | 1.26467E–19 |
| miR-21-5p | miR-21 | 854585 | 1.717 | 9.28451E–09 | 1.9336E–08 |
| miR-106b-3p | miR-106b | 2614 | 1.091 | 9.0971E–06 | 7.14346E–06 |
| let-7c-5p | let-7c | 27205 | –1.896 | 0.0002 | 8.76786E–05 |
| miR-7-1-5p | miR-7-1 | 93 | 0.968 | 0.0005 | 0.0002 |
| miR-205-5p | miR-205 | 25289 | 1.956 | 0.0049 | 0.0015 |
| miR-25-3p | miR-25 | 47417 | 0.656 | 0.0801 | 0.0165 |
| miR-486-5p# | miR-486-2# | 475 | –0.645 | 1.8177 | 0.2466 |
| miR-486-5p# | miR-486-1# | 473 | –0.593 | 2.3635 | 0.3102 |
| miR-451a | miR-451a | 3849 | –0.221 | 6.7117 | 0.7409 |
| miR-146a-5p | miR-146a | 482 | –0.058 | 8.8212 | 0.9087 |
Abbreviations: FDR false discovery rate, MIBC muscle-invasive bladder cancer.
Significant results in bold.
#for this miRNA it was not possible to distinguish the locus.