Table 2. Nucleotide and amino acid changes generated from the colon cancer mutation array test.
Types | Gene | Nucleotide change | Amino acid change | Genotype |
---|---|---|---|---|
CD166 positive CRC | ||||
Carcinoma | FBXW7 | c.1393C>T | p.R465C | Mutant |
Carcinoma | TP53 | c.527G>T | p.C176F | Mutant |
Carcinoma | KRAS | c.436G>A | p.A146T | Mutant |
CD166 negative CRC | ||||
Carcinoma | TP53 | c.527G>A | p.C176Y | Mutant |
CD166 positive CAD | ||||
Adenoma | APC | c.4081_4082delCC | p.P1361fs*13 | Mutant |
Adenoma | APC | c.4391_4394delAGAG | p.E1464fs*8 | Mutant |
Adenoma | APC | c.4118_4118delC | p.P1373fs*42 | Mutant |
Adenoma | APC | c.4216C>T | p.Q1406* | Mutant |
Adenoma | APC | c.3916G>T | p.E1306* | Mutant |
Adenoma | APC | c.3956delC | p.P1319fs*2 | Mutant |
Adenoma | KRAS | c.436G>A | p.A146T | Mutant |
Adenoma | KRAS | c.35G>A | p.G12D | Mutant |
Adenoma | KRAS | c.34G>A | p.G12S | Mutant |
Adenoma | SRC | c.1591C>T | p.Q531* | Mutant |
Adenoma | TP53 | c.473G>A | p.R158H | Mutant |
Adenoma | PIK3CA | c.1633G>A | p.E545K | Mutant |
CD166 negative CAD | ||||
Adenoma | APC | c.4081_4082delCC | p.P1361fs*13 | Mutant |