Table 1. Demographic, clinical and molecular pathology characteristics of the patients enrolled in the clinical trial.
CODE | Sex | ECOG | Metastatic sites | Previous treatment lines | K-ras | HLA | Treatment courses | MANT | Type of response |
---|---|---|---|---|---|---|---|---|---|
MFA/A/DL1 | F | 0 | Liver, lung | 11 | Wt | A2 | 3 | Na | SD |
RAA/A/DL1 | F | 0 | Peritoneum, nodes | 7 | Wt | A2 | 3 | Na | PD |
ASA/A/DL1 | M | 0 | Liver, Lung | 3 | Wt | A2 | 3 | Na | SD |
LVA/A/DL2 | M | 0 | Liver, Lung, nodes | 7 | Wt | A11 | 6 | Na | SD |
SGA/A/DL2 | M | 0 | Peritoneum, nodes | 4 | Wt | A25 | 6 | Na | SD |
ZSA/A/DL3 | F | 0 | Nodes, Adrenal | 3 | Wt | A2 | 48 | Na | PR |
PNA/A/DL3 | F | 0 | Lung, bones | 3 | Mut | A1 | 3 | Na | SD |
SNA/A/DL3 | M | 2 | Liver, lung | 3 | Mut | A2 | 3 | Na | PD |
GL/B/DL2 | F | 0 | Liver, abdomen | 3 | Mut | A24 | 3 | Na | PD |
PP/B/DL2 | F | 0 | Lung, liver abdomen | 3 | Wt | A2 | 3 | Na | SD |
FG/B/DL2 | M | 0 | Abdomen, nodes | 3 | Wt | A24 | 3 | Na | PD |
MM/B/DL3 | M | 1 | Lung, liver abdomen | 3 | Mut | A1 | 3 | Na | SD |
LM/C/DL1 | F | 2 | Peritoneum, lung, liver | 2 | Mut | A24 | 7 | 2 | SD |
CV/C/DL1 | M | 1 | Peritoneum, lung, liver | 6 | Mut | A3 | 6 | 0 | PD |
BF/C/DL1 | M | 2 | Peritoneum, lung, liver | 3 | Mut | A11 | 3 | 0 | PD |
CL/C/DL2 | F | 0 | Peritoneum, nodes | 3 | Mut | A2 | 12 | 1 | PD |
FA/C/DL2 | F | 2 | Colon, lung, liver | 6 | Wt | A11 | 11 | 0 | SD |
SA/C/DL2 | M | 0 | Lung, liver, nodes | 5 | Wt | A2 | 12 | 2 | PR |
SS/C/DL3 | F | 0 | Brain, lung, liver, nodes | 5 | Mut | A23 | 12 | 3 | PR |
BA/C/DL3 | F | 1 | Colon, lung, liver, nodes | 2 | Mut | A2 | 11 | 0 | SD |
SA/C/DL3 | F | 2 | Peritoneum, lung, liver | 5 | Mut | A2 | 12 | 0 | PD |
DA/C/DL3 | F | 2 | Peritoneum, lung, liver | 4 | Mut | A1 | 10 | 0 | PD |
MP/C/DL3 | M | 1 | Peritoneum, lung, liver | 6 | Mut | A2 | 6 | 0 | SD |
PM/C/DL3 | M | 1 | Peritoneum, lung, liver | 2 | Mut | A11 | 12 | 3 | SD |
MU/C/DL3 | F | 1 | Soft tissue, nodes | 2 | Wt | A24 | 12 | 14 | SD |
PA/C/DL3 | M | 1 | Peritoneum, lung, liver | 7 | Wt | A2 | 11 | 3 | PR |
CA/C/DL3 | M | 2 | Peritoneum, lung, liver | 3 | Mut | NA | 6 | 0 | PD |
BG/C/DL3 | F | 0 | Peritoneum, lung, liver | 3 | Wt | A2 | 10 | 8 | SD |
NR/C/DL3 | F | 2 | Peritoneum, lung, liver | 2 | Mut | A2 | 3 | 0 | PD |
SR/C/DL0 | M | 0 | Lung, liver | 3 | Wt | A23 | 12 | 5 | SD |
DG/C/DL0 | F | 0 | Lung, liver | 3 | Wt | A33 | 10 | 5 | PR |
BL/C/DL0 | F | 0 | Lung, liver | 2 | Wt | A3 | 10 | 9 | SD |
ML/C/DL0 | F | 0 | Peritoneum, lung, liver | 2 | Mut | A2 | 10 | 9 | SD |
VP/C/DL0 | M | 1 | lung, liver | 2 | Wt | A2 | 7 | 1 | PD |
PG/C/DL0 | M | 1 | lung, liver | 2 | Wt | A24 | 9 | 12 | SD |
SA/C/DL0 | M | 2 | Peritoneum, lung, liver | 3 | Wt | A1 | 7 | 0 | PD |
MA/C/DL0 | M | 0 | lung, liver | 2 | Mut | A1 | 9 | 32 | PR |
PA/C/DL0 | M | 0 | lung, liver | 2 | Wt | A3 | 11 | 14 | PR |
DL/C/DL0 | F | 0 | Peritoneum, lung, liver | 3 | Wt | A2 | 9 | 4 | SD |
VC/C/DL0 | M | 0 | Peritoneum, lung, liver | 2 | mut | A23 | 10 | 7 | PR |
PA/C/DL0 | F | 1 | Peritoneum, lung, liver | 3 | Wt | A23 | 9 | 4 | SD |
Legend: ECOG, Eastern Cooperative Oncology Group performance status; Wt, Wild type; Mut, Mutated; SD, Stabilized Disease; PR, Partial Response; PD, Progressive Disease; MANT, Maintainance Therapy duration in months; Na; not achieved.