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. Author manuscript; available in PMC: 2019 Jan 4.
Published in final edited form as: Cell Stem Cell. 2017 Dec 14;22(1):119–127.e3. doi: 10.1016/j.stem.2017.11.009

Figure 4. MuSCs follow a model of population asymmetry and neutral drift with repeated injury.

Figure 4

(A) Composite images of GFP+ myonuclei in regenerated muscles following serial BaCl2 injury. Scale bar, 100 µm.

(B-C) Quantification of GFP+ myofiber cluster density and the number of regenerated myofibers per cluster following serial BaCl2 injury (n = 5).

(D) Cumulative, scaled cluster size distribution following serial BaCl2 injury (199-446 clusters).

(E-F) Quantification of nearest neighbor index and cumulative distribution frequency derived from spatial analyses of GFP+ nuclei following serial BaCl2 injury (n = 5).

Data are represented as average ± SEM (***P < 0.001, **P < 0.01, *P < 0.05). See also Figure S4.