Table 4. Hazard ratio and 95% CI of risk of ischemic stroke by intake of saturated fat for race, sex, BMI, mean saturated fat intake, and follow-up duration.
Outcome | Studies (n) | HR | 95% CI | P value | I-squared | |
---|---|---|---|---|---|---|
Ischemic stroke | 11 | 0.89 | 0.82 | 0.96 | 0.004 | 38.9 |
Race | ||||||
Japanese | 4 | 0.82 | 0.71 | 0.93 | 0.003 | 19.0 |
Non-Japanese | 7 | 0.93 | 0.84 | 1.03 | 0.172 | 41.7 |
Sex | ||||||
Women | 4 | 1.04 | 0.90 | 1.21 | 0.586 | 5.0 |
Men | 3 | 0.85 | 0.74 | 0.97 | 0.018 | 35.9 |
Mixed | 4 (all Japanese) | 0.82 | 0.71 | 0.93 | 0.003 | 19.0 |
BMI | ||||||
< 24 | 4 (all Japanese) | 0.82 | 0.71 | 0.93 | 0.003 | 19.0 |
≥ 24 | 7 | 0.93 | 0.84 | 1.03 | 0.172 | 41.7 |
Mean saturated fat intake | ||||||
< 25 g/d | 8 (4 Japanese) | 0.92 | 0.83 | 1.02 | 0.111 | 43.3 |
≥ 25 g/d | 3 | 0.85 | 0.75 | 0.96 | 0.010 | 36.2 |
Follow-up duration | ||||||
< 14 years | 5 (1 Japanese) | 0.96 | 0.86 | 1.07 | 0.441 | 27.2 |
≥ 14 years | 6 (3 Japanese) | 0.79 | 0.70 | 0.90 | 0.000 | 11.2 |
BMI, body mass index; CI, confidence interval; HR, hazard ratio