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. 2018 May 1;25(5):422–429. doi: 10.5551/jat.42242

Table 3. Solution for fixed effects as a result of stepwise method to identify factors affecting the percentage change in LDL-C from the combined dataset of Japanese and European study.

Effect Study Identifier Dose Estimate SEM p value
Intercept −25.1534 12.1494 0.0428
Dose 1 mg 9.0138 5.8351 0.1278
Dose 2 mg 0
Baseline LDL-C −0.04628 0.03183 0.1513
Age −1.0615 0.8811 0.2331
Body Weight 0.3086 0.1294 0.0203
Study Identifier European study 2.7080 4.9292 0.5848
Study Identifier Japanese study 0
Dose*Study Identifier European study 1 mg −1.8201 6.6207 0.7843
Dose* Study Identifier Japanese study 1 mg 0
Dose* Study Identifier European study 2 mg 0
Dose* Study Identifier Japanese study 2 mg 0

SEM, standard error of mean