TABLE 1.

Relative distribution and basal activity of AMPK heterotrimeric complexes detected in human and mouse skeletal muscle

Trimer complex			Mus musculus
	Homo sapiens vastus lateralis		Extensor digitorum longus		Soleus
	Relative expression	Relative basal activity	Relative expression	Relative basal activity	Relative expression	Relative basal activity
α2β2γ1	∼65%	∼30%	∼70%	∼50%	∼60%	∼35%
α2β2γ3	∼20%	<5%	∼20%	∼20%	<2%	<2%
α1β2γ1	∼15%	∼65%	<5%	∼25%	∼20%	∼50%
α2β1γ1	N.D.	N.D.	<3%	<5%	∼10%	<15%
α1β1γ1	N.D.	N.D.	<2%		<8%

The composition of AMPK heterotrimeric complexes was estimated from immunoprecipitation experiments in extensor digitorum longus and soleus from C57BL/6 mice as well as human male vastus lateralis. Values adapted from references 70, 76, and 487. N.D., nondetectable.