Fig. 6. MSC-derived STC2 reduced the CD8⁺ Tc 1 cells by regulating the activity of HO-1.

a The diagrammatic sketch of deletion constructs of human STC2. b The activities of HO-1 were evaluated by the production of CO using a hemoglobin-degradation test, and the bar chart showed the relative level of HO-1 activity. c Representative dot plots of the alterations of IFN-γ-producing CD8⁺ T cells were evaluated by flow cytometry, and bar chart showed the quantification (d). Data are presented as the mean ± SEM (n = 5); *p < 0.05 and **p < 0.01