Fig. 1. Loss of miR-501-3p coincided with metastasis and prognosis of HCCs.

a Expression of miR-501-3p in five established HCC cell lines was determined by qRT-PCR. b Expression of miR-501-3p in HCC tissues with or without recurrence after surgical resection was determined by qRT-PCR. **P < 0.01. c Expression of miR-501-3p in HCC tissues with or without metastasis after surgical resection was determined by qRT-PCR. **P < 0.01. d Kaplan–Meier’s analysis showed that HCC patients with overexpression of miR-501-3p exhibited better overall survival and a lower cumulative recurrence rate compared with those who had low expression of miR-501-3p. Data depicts the mean ± standard deviation and are representative of three independent experiments. HR hazard ratio