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. 2018 May 10;9(5):535. doi: 10.1038/s41419-018-0577-y

Fig. 2. miR-501-3p inhibits the proliferation, migration and invasion of HCC cells in vitro.

Fig. 2

a Expression of miR-501-3p in HCCLM3 and PLC/PRF/5 cells that were transfected with corresponding vectors was determined by qRT-PCR. b CCK-8 assay was performed to detect cell proliferation. *P < 0.05. c Wound-healing migration assays and the quantification of the percentage of open area were shown. Scale bar: 100 μm, **P < 0.01. d Invasive behavior was tested using transwell invasion assays after overexpression or knockdown of miR-501-3p in HCC cells. Scale bar: 100 μm, **P < 0.01. Data depicts the mean ± standard deviation and are representative of three independent experiments