Figure 2.

Somatic mutation landscape of FFPE and ctDNA samples. (A) The bars represent the non-silent mutational number of each sample. The samples are sorted by the tumour stage [benign, stage I (AIS/MIA, adenocarcinoma), and stage II–III] and number of non-silent mutations. Mutational type is distinguished by colour. ctDNA mutational landscape is shown in (B). The major clinical information (plasma, gender, tumour stage, cancer subtype) is shown in (C). ctDNA, circulating tumour DNA; AIS, adenocarcinoma in situ; MIA, minimally invasive adenocarcinoma; FFPE, formalin-fixed, paraffin embedded.