Table 1.

Applied acoustic power and energy, estimated thermal dose volume (V_240EM), and maximum recorded tissue temperature for 27 separate sonications using from 2 mm to 12 mm diameter cells for exposure durations ranging from 16 to 36 s in ex-vivo lamb legs (n = 6)

Cell diameter/exposure duration	Power (W)	Energy (kJ)	V240EM (cm3)	Maximum temperature (°C)
2 mm/16 s	90	1.44	0.83	81.2
	120	1.92	2.63	67.2
	150	2.40	3.06	94.9
	190	3.04	3.57	112.4
	190	3.04	2.87	101.4
4 mm/16 s	20	0.32	0.00	42.1
	40	0.64	0.15	61.7
	60	0.96	0.16	67.2
	80	1.28	0.65	71.6
	120	1.92	0.74	77.1
	150	2.40	4.10	92.6
	160	2.56	2.28	113.6
	190	3.04	2.59	98.9
	190	3.04	4.12	113.2
8 mm/20 s	20	0.40	0.03	62.5
	40	0.80	0.39	58.8
	40	0.80	0.61	54.6
	60	1.20	1.16	69.1
	80	1.60	0.90	68.8
	120	2.40	3.36	77.1
	150	3.00	5.14	78.7
	150	3.00	4.38	81.8
12 mm/36 s	20	0.72	0.21	59.7
	40	1.44	2.72	89.9
	60	2.16	3.92	74.1
	80	2.88	5.46	81.2
	80	2.88	5.75	81.1

In each case, the highest power exposure was delivered in two different samples