Fig. 7. Corylin enhances etoposide (VP16)-induced apoptosis through lncRNA RAD51-AS1-mediated inhibition of DNA damage repair.
a The xenograft tumors were excised from the mice at the end of the experiment. Histological analysis was performed using H&E staining and in situ hybridization for the detection of RAD51-AS1 level. b Immunohistochemical staining represented the effect of corylin and etoposide (VP16) on RAD51, cleaved caspase 3 (cl-caspase 3), and cleaved caspase 9 (cl-caspase 9) protein expression in mice xenograft tumors. Magnification: ×400