Table 2.
Comparison of studied parameters, depending on 25(OH)D serum concentration in subjects treated with acenocoumarol (AC) (the cut-off value set at 20 ng/mL was used to define the deficiency level).
| Characteristics | Subjects receiving AC with 25(OH)D < 20 ng/mL | Subjects receiving AC with 25(OH)D ≥ 20 ng/mL | p |
|---|---|---|---|
| Number, n | 27 | 31 | |
| Age, years | 65 (60; 73) | 65 (59; 73) | NS |
| Gender (males/females), n (%) | 8 (29.6)/19 (70.4) | 19 (61.3)/12 (38.7) | 0.015 |
| Body mass index, kg/m2 | 27.9 (24.8; 31.2) | 28.4 (24.9; 32) | NS |
| Post-menopause, years | 15 (8.8; 24) | 15 (8.5; 19.8) | NS |
| Smokers/non-smokers, n (%) | 3 (11.1)/24 (88.9) | 8 (25.8)/23 (74.2) | NS |
| Duration of AC treatment, years | 8 (6; 10) | 10 (7; 13) | NS |
| Weekly dose of AC, mg | 21 (17; 31) | 17 (12; 28) | 0.045 |
| Serum 25(OH)D, ng/mL | 17.2 (14.8; 18.6) | 25.6 (22.6; 29.6) | <0.001 |
| ALP, IU/L | 62 (58; 76) | 59 (52; 74) | NS |
Results are shown as median and quartiles (Q1; Q3).