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. 2018 May 3;12:29. doi: 10.3389/fncom.2018.00029

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Copyright © 2018 Felton, Yu, Boothe, Oie and Franaszczuk.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Electrical coupling between distal apical dendrite and soma. (A) current injections to distal apical dendrite (green arrow) and soma compartments (black arrow) (neuron rendering from Traub et al., 2005) (B, left) model response to 3 nA, 5 ms step current injection into soma when hot zone is in-place. (B, right) Model response to 3 nA, 5 ms somatic step current and EPSP-like current injection to distal apical dendrite (1 nA peak, 5 ms delay relative to somatic step current) when hot zone is in-place. (C, left) Model response to 3 nA, 5 ms step current injection into soma without hot zone. (C, right) Model response to 3 nA, 5 ms somatic step current and EPSP-like current injection to distal apical dendrite (1 nA peak, 5 ms delay relative to somatic step current) without hot zone.