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. 2018 May 4;5:134. doi: 10.3389/fmed.2018.00134

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Copyright © 2018 Tseng, Kim, Li and Cho.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Myeloperoxidase (MPO) is important for tissue damage in I/R-induced hepatic injury. Hepatic injury was induced by I/R as described in Section “Materials and Methods.” (A,B) Neutrophils in the liver sections were stained with an esterase kit (pink) and counterstained with hematoxylin (purple). (B) The number of transmigrated neutrophils in the interstitial space. (C) Serum levels of aspartate aminotransferase (AST). Data are shown as the mean ± SD. **P < 0.01, ***P < 0.001, or ****P < 0.0001 after analysis of variance and Tukey’s test.