Fig. 2.

Ureido-substituted benzenesulfonamides bound in the active site of hCA II (grey). A) Compound U-CH₃ (pink) B) Compound U-F (green) and C) Compound U-NO₂ (yellow) with active site residues and relative bond distances (Å) labeled. Specific interactions of compounds with the active site of hCA II are indicated as black dotted lines and hydrophobic interactions shown as red dotted lines. The zinc (magenta) and solvent (red) are represented as spheres. The figure was made using PyMol.26. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)