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. 2018 Mar 23;7(4):24. doi: 10.3390/cells7040024

Table 3.

Different drugs across the blood–brain barrier.

Drug Structure The Method of Across the BBB Function Reference
cis-Dichlorodiamineplatinum graphic file with name cells-07-00024-i001.jpg Ultrasound alkylating agent, Antitumor Effect [53,54]
Barbital graphic file with name cells-07-00024-i002.jpg Lipophilic prodrug Sedative-hypnotics, sedative-hypnotic, antiepileptic and anticonvulsant effect [55,56]
5-fluorouracil graphic file with name cells-07-00024-i003.jpg Chemical delivery systems Antineoplastic [57,58]
Adriamycin graphic file with name cells-07-00024-i004.jpg Liposomes Antitumor antibiotics [59,60,61]
Idebenone graphic file with name cells-07-00024-i005.jpg Sold liposome nanoparticles Anti-senile dementia drug and mental symptoms drug [62,63]
Saquinavir graphic file with name cells-07-00024-i006.jpg Nanocarriers Antivirals. For selective HIV protease inhibitors. [64]
Rivastigmine graphic file with name cells-07-00024-i007.jpg Nanocarriers Acetylcholinesterase inhibitor [65]
Idebenone, IDBN graphic file with name cells-07-00024-i008.jpg Nanocarriers Alzheimer’s disease and cognitive defects [66]
Curcumin graphic file with name cells-07-00024-i009.jpg Liposomes Antineoplastic [67]