Table 3.
Biological processes affected by the predicted mRNA targets of miR-2137 1.
| Biological Processes | p-Values |
|---|---|
| regulation of transcription from RNA polymerase II promoter (GO: 0006357) | <0.01 |
| transcription from RNA polymerase II promoter (GO: 0006366) | <0.01 |
| developmental process (GO: 0032502) | <0.01 |
| muscle organ development (GO: 0007517) | 0.01 |
| transcription, DNA-dependent (GO: 0006351) | 0.01 |
| segment specification (GO: 0007379) | 0.01 |
| nervous system development (GO: 0007399) | 0.01 |
| system development (GO: 0048731) | 0.02 |
| RNA metabolic process (GO: 0016070) | 0.02 |
| mesoderm development (GO: 0007498) | 0.05 |
| ectoderm development (GO: 0007398) | 0.05 |
1 Predicted mRNA targets, which have a context++ score ≤−0.2, were obtained from TargetScan (Version 7.1) [28] and were included in the gene ontology (GO) analysis. The gene ontology analysis was done using PANTHER (Version 11.1) [31,32] with Bonferroni correction, and p ≤ 0.05 was considered statistically significant.