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. 2018 Mar 29;10(4):428. doi: 10.3390/nu10040428

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Sequential change in the levels of Hb, serum ferritin and hepcidin-25 in OIT-responders during OIT. The levels of Hb rose linearly with a peak at 5 months after OIT and then slightly decreased at the end of the study. Serum levels of ferritin were decreased from baseline at 1 month, and then rose continuously from 2 to 7 months after OIT. Serum levels of hepcidin-25 were similar to baseline at 6 months but significantly increased at the end of the study. Serum levels of hepcidin-25 were positively correlated with those of ferritin in the OIT-responders (r = 0.869, p = 0.0002). Data are expressed as mean ± SEM. Comparison of 2 means was determined by the Man–Whitney U test. # p < 0.01, vs. data at 0 month.