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Effects of blackcurrant anthocyanins and 17β-estradiol (E2) on mRNA levels of estrogen-dependent genes. TIG113 cells were treated with the indicated anthocyanins (10 μM), BCE (1.0 or 10.0 μg/mL), or E2 (1 nM) for 24 h. mRNA levels of (A) COL1A1, (B) COL3A1, (C) ELN, (D) HAS3, (E) HYAL3, (F) MMP12, and (G) TIMP3 were quantified by RT-qPCR. Data represent the means ± standard errors of the mean of at least three independent experiments; * p < 0.05 vs. untreated control cells.
