Table 3.
Prevalence of Different Types of MCI According Risk Factors.
| aMCI n (%) |
naMCI n (%) |
mdaMCI n (%) |
namdMCI n (%) |
Any MCI n (%) |
|
|---|---|---|---|---|---|
| HTN+ (n = 225) | 28 (12.4) | 29 (12.8) | 9 (4.0) | 10 (4.4) | 50 (22.2) |
| HTN– (n = 626) | 51 (8.1) | 61 (9.7) | 14 (2.2) | 21 (3.3) | 64 (10.2) |
| OR (95% CI) | 1.60 [0.97, 2.58] | 1.37 [0.86, 2.18] | 1.84 [0.75, 4.19] | 1.34 [0.65, 2.91] | 2.51 [1.68, 3.76]* |
| DM+ (n = 39) | 8 (20.5) | 2 (5.1) | 2 (5.1) | 3 (7.6) | 9 (23.1) |
| DM– (n = 812) | 71 (8.7) | 88 (10.8) | 21 (2.6) | 28 (3.4) | 105 (12.9) |
| OR (95% CI) | 2.69 [1.25, 5.98]§ | 0.44 [0.10, 1.71] | 2.04 [0.46, 8.31] | 2.33 [0.72, 7.11] | 2.02 [0.93, 4.22] |
| HLD+ (n = 65) | 10 (15.4) | 3 (4.6) | 2 (3.1) | 0 (0.0) | 10 (15.3) |
| HLD– (n = 786) | 69 (8.8) | 87 (11.1) | 21 (2.7) | 31 (4.0) | 104 (13.2) |
| OR (95% CI) | 1.89 [0.93, 3.72] | 0.39 [0.13, 1.19] | 1.16 [0.26, 4.52] | 0.00 [0.00, 1.28] | 1.35 [0.66, 2.70] |
| Smoking+ (n = 201) | 8 (4.0) | 18 (8.9) | 4 (2.0) | 4 (2.0) | 22 (10.9) |
| Smoking– (n = 650) | 71 (10.9) | 72 (11.1) | 19 (2.9) | 27 (4.1) | 92 (14.1) |
| OR (95% CI) | 0.34 [0.16, 0.70]† | 0.79 [0.46, 1.35] | 0.67 [0.24, 1.92] | 0.47 [0.17, 1.32] | 0.74 [0.45, 1.21] |
Note. Any MCI = MoCA < 22; MCI = mild cognitive impairment; aMCI = amnestic MCI; naMCI = nonamnestic MCI; mdaMCI = multidomain MCI; namdMCI = nonamnestic multidomain MCI; HTN = hypertension; OR = odds ratio; CI = confidence interval; DM = diabetes mellitus; HLD = hyperlipidemia; MoCA = Montreal Cognitive Assessment.
‡
nonsignificant p < .1. *p < .0001. ‡p < .001. †p < .01. §p < .05.