Table 2.
Comprehensive behavioral test battery of Rapgef2-cKO mice
| Test | Age (w) |
|---|---|
| 1. General health | 17–23 |
| 2. Light/dark transition | 17–24 |
| 3. Open field | 18–24 |
| 4. Elevated plus-maze | 18–24 |
| 5. Hot plate | 19–25 |
| 6. Social Interaction (novel environment) | 19–25 |
| 7. Rotarod | 19–26 |
| 8. Social Interaction (Crawley version) | 22–29 |
| 9. Prepulse inhibition | 23–30 |
| 10. Porsolt forced swim | 24–30 |
| 11. Barnes maze (training) | 42–52 |
| 12. Barnes maze (probe test (24 h)) | 46–52 |
| 13. Barnes maze (probe test (1 month)) | 51–57 |
| 14. T-maze (forced alternation with fasting) | 60–66 |
| 15. T-maze (left-right discrimination) | 61–69 |
| 16. Tail suspension test | 63–69 |
| 17. Fear conditioning test (Day 1) | 63–70 |
| 18. Fear conditioning test (Day 2) | 64–70 |
| 19. Fear conditioning test (Day 31) | 68–74 |
| 20. Social Interaction (home cage) | 69–76 |
| 21. Open field | 72–78 |
Age (w) age in weeks of mice at the beginning of each test listed