Table 3.
Comprehensive behavioral test battery of Rapgef6-KO mice
| Test | Age (w) |
|---|---|
| 1. General health | 14–16 |
| 2. Rotarod | 20–22 |
| 3. Hot plate | 18–19 |
| 4. Open field | 15–17 |
| 5. Light/dark transition | 15–16 |
| 6. Elevated plus-maze | 17–19 |
| 7. Porsolt forced swim | 32–34 |
| 8. Tail suspension test | 41–42 |
| 9. Prepulse inhibition | 32–33 |
| 10. Social Interaction (novel environment) | 19–20 |
| 11. Social Interaction (home cage) | 59–62 |
| 12. Social Interaction (Crawley version) | 31–33 |
| 13. Barnes maze (training) | 32–36 |
| 14. Barnes maze (probe test (24 h)) | 34–36 |
| 15. Barnes maze (probe test (1 month)) | 39–40 |
| 16. T-maze (forced alternation without fasting) | 39–42 |
| 17. Fear conditioning test (Day 1) | 41–43 |
| 18. Fear conditioning test (Day 2) | 41–43 |
| 19. Fear conditioning test (Day 36) | 46–48 |
Age (w) age in weeks of mice at the beginning of each test listed