Table 2.
Top SNPs associated with plasma NFL levels (P values < 10− 5)
CHR | SNP | MAF | Closest Gene | SNP Type/Location | P values |
---|---|---|---|---|---|
11 | rs7943454 | 0.460 | LUZP2 | intron | 1.39 × 10−6 |
5 | rs640476 | 0.297 | GABRB2 | intergenic | 6.71 × 10−6 |
Abbreviations: CHR chromosome, LUZP2 leucine zipper protein 2, MAF minor allele frequency, SNP single nucleotide polymorphism, GABRB2 gamma-aminobutyric acid type A receptor beta2 subunit