Table 2.
Associations with incident all-cause and cardiovascular disease (CVD) mortality for coronary artery calcification measures analyzed in independent models in European American and African American participants with type 2 diabetes
| Outcome | CAC measure | European Americans | African Americans | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Hazard ratio | 95% confidence interval | p-value | n | Hazard ratio | 95% confidence interval | p-value | n | ||||
| All-cause mortality | Volume (90 HU) | 1.67 | 1.37 | 2.03 | 3.08 × 10−7 | 902 | 1.48 | 1.14 | 1.92 | 0.003 | 552 |
| All-cause mortality | Agatston score (90 HU) | 1.65 | 1.35 | 2.02 | 1.02 × 10−6 | 901 | 1.45 | 1.12 | 1.88 | 0.005 | 551 |
| All-cause mortality | Agatston score (130 HU) | 1.54 | 1.27 | 1.87 | 1.42 × 10−5 | 816 | 1.27 | 1.01 | 1.61 | 0.046 | 446 |
| All-cause mortality | Density (90 HU) | 1.31 | 1.12 | 1.53 | 6.98 × 10−4 | 889 | 1.13 | 0.92 | 1.38 | 0.233 | 552 |
| CVD mortality | Volume (90 HU) | 1.93 | 1.45 | 2.57 | 6.58 × 10−6 | 887 | 2.00 | 1.25 | 3.21 | 0.004 | 544 |
| CVD mortality | Agatston score (90 HU) | 1.86 | 1.39 | 2.49 | 3.46 × 10−5 | 886 | 1.98 | 1.25 | 3.13 | 0.004 | 543 |
| CVD mortality | Agatston score (130 HU) | 1.68 | 1.25 | 2.27 | 5.74 × 10−4 | 801 | 1.84 | 1.20 | 2.84 | 0.006 | 438 |
| CVD mortality | Density (90 HU) | 1.39 | 1.13 | 1.70 | 0.002 | 875 | 1.26 | 0.95 | 1.66 | 0.106 | 544 |
Hazard ratios for mortality associations reported per standard deviation change in coronary artery calcification measures. Models adjusted for age, sex, statin use, total cholesterol, HDL, systolic blood pressure, high blood pressure medication use, and current smoking; analyses additionally adjusted for study (Diabetes Heart Study or African American Diabetes Heart Study) in African Americans
HU Hounsfield unit