Table 1.
Characteristics of pregnant women infected with HIV at CAISM/UNICAMP from 2000 to 2015
Characteristics | n | Median (%) |
---|---|---|
Age (years) | 793 | 28 (13–46) |
Parity | 793 | 1 (0–9) |
Schooling years (n = 769) | ||
< 8 | 468 | 60.9 |
8–11 yrs. | 248 | 32.2 |
> 12 | 39 | 5.1 |
No schooling | 14 | 1.8 |
Ethnicity: White | 485 | 61.2 |
HIV diagnosis (n = 789) | ||
Prior to pregnancy | 489 | 62.5 |
During pregnancy | 294 | 37.5 |
In use of ART at conception (n = 787) | 217 | 27.6 |
In use of Efavirenz at conception (n = 793) | 81 | 10.2 |
Planned pregnancy (n = 382) | 98 | 25.7 |
Heterosexual transmission (n = 408) | 380 | 93.1 |
Opportunistic disease during pregnancy (n = 785) | 32 | 4.1 |
First CD4 median (cel/ml) | 734 | 444 (3–1915) |
Peripartum CD4 median (cel/ml) | 175 | 552 (5–2164) |
Median time of ART use (days) | 410 | 152.5 (4–292) |
Peripartum Viral Load < 50 (copies/ml) (n = 732) | 432 | 58.9 |
CDC classification (n = 758) | ||
1 | 227 | 29.9 |
2 | 391 | 51.6 |
3 | 140 | 18.5 |
Coinfections during pregnancy (n = 787) | 667 | 84.8 |
Obstetrics complications (n = 792) | 417 | 52.7 |
ART adherence during prenatal care | 649 | 84.3 |
Changed ART (n = 776) | 149 | 19.2 |
Premature rupture of membranes (n = 773) | 121 | 15.7 |
Labor (n = 447) | 188 | 42.1 |
Intravenous AZT (n = 775) | 735 | 94.8 |
Antiretroviral regimens during pregnancy (n = 793) | ||
None | 15 | 1.9 |
Monotherapy with AZT | 23 | 2.9 |
NRTI + NRTI | 11 | 1.4 |
NRTI + NRTI + NVP | 138 | 17 |
NRTI + NRTI + NFV | 135 | 17 |
NRTI + NRTI + LPV/R | 428 | 54 |
Regimens with other PI | 40 | 5 |
NRTI + NRTI + EFV | 3 | 0.4 |
TOTAL | 793 | 100 |
ART antiretroviral therapy, AZT zidovudine, NRTI nucleos(t)ide reverse transcriptase inhibitors, NNRTI non-nucleoside reverse transcriptase inhibitor, NVP nevirapine, EFV efavirenz, PI protease inhibitor, NFV nelfinavir, LPV lopinavir, R ritonavir, CDC Centers for Disease Control and Prevention