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. 2018 May 11;16:46. doi: 10.1186/s12958-018-0364-8

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Gene and protein expression of Matrix Metalloproteinase (MMP) and Extracellular Matrix (ECM) family. Results are presented as fold change with NTC as the reference, mean ± SEM of three independent experiments from each of three independent infections. P-value < 0.05 is indicated by an asterisk. a MMP family. Gene target RT-PCR relative expression of MMP family genes in fibroid and myometrial cells upregulated with miR-21. b ECM Family. Gene target RT-PCR relative expression of ECM family genes in fibroid and myometrial cells upregulated with miR-21. c Collagen Assay. ELISA results of Collagen 1A1 protein expression in fibroid and myometrial cells upregulated with miR-21