Table 4.
Least squares (LS) means scoresa (95% Confidence intervals, CIs) of HRQoL according to quartiles of Western dietary pattern in breast cancer survivors
| Quartiles of Western dietary pattern | ||||||
|---|---|---|---|---|---|---|
| Variables | N (=232) | Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | P for trend |
| EORTC QLQ - C30 | ||||||
| Global health status/QoL | 200 | 33.35 (23.82 - 46.70) | 36.10 (25.92 - 50.27) | 34.29 (24.56 - 47.89) | 43.52 (31.43 - 60.25) | 0.22 |
| Functioning | ||||||
| Physical Functioning | 228 | 67.65 (60.64 - 75.46) | 77.67 (69.77 - 86.45) | 81.89 (73.67 - 91.03) | 77.41 (69.47 - 86.24) | 0.06 |
| Role Functioning | 229 | 57.02 (45.20 - 71.93) | 70.04 (55.73 - 88.02) | 79.94 (63.68 - 100.34) | 70.20 (55.45 - 88.88) | 0.15 |
| Emotional Functioning | 230 | 63.32 (52.75 – 76.00) | 70.77 (59.14 - 84.69) | 77.86 (65.12 - 93.10) | 66.73 (55.55 - 80.15) | 0.61 |
| Cognitive Functioning | 230 | 74.49 (65.26 - 85.03) | 70.71 (62.09 - 80.53) | 78.88 (69.30 - 89.78) | 73.62 (64.47 - 84.06) | 0.86 |
| Social Functioning | 230 | 62.80 (50.07 - 78.78) | 61.88 (49.52 - 77.32) | 66.70 (53.43 - 83.26) | 53.96 (42.98 - 67.73) | 0.34 |
| Symptom | ||||||
| Fatigue | 229 | 25.62 (18.52 - 35.43) | 20.78 (15.17 - 28.46) | 22.48 (16.42 - 30.77) | 23.91 (17.34 - 32.96) | 0.88 |
| Nausea and vomiting | 230 | 4.96 (3.15 - 7.82) | 2.53 (1.62 - 3.95) | 2.17 (1.39 - 3.39) | 3.84 (2.43 - 6.06) | 0.46 |
| Pain | 229 | 12.87 (7.72 - 21.45) | 8.12 (4.94 - 13.33) | 8.19 (4.99 - 13.44) | 8.22 (4.95 - 13.63) | 0.21 |
| Dyspnea | 228 | 4.23 (2.45 - 7.30) | 6.61 (3.89 - 11.22) | 3.76 (2.21 - 6.39) | 4.50 (2.62 - 7.73) | 0.78 |
| Insomnia | 228 | 24.84 (14.51 - 42.52) | 11.00 (6.52 - 18.55) | 16.76 (9.96 - 28.19) | 18.81 (11.04 - 32.05) | 0.75 |
| Loss of appetite | 228 | 3.33 (1.98 - 5.61) | 3.08 (1.85 - 5.11) | 2.64 (1.59 - 4.37) | 3.65 (2.18 - 6.13) | 0.83 |
| Constipation | 228 | 4.44 (2.56 - 7.70) | 4.46 (2.61 - 7.60) | 4.67 (2.74 - 7.96) | 8.09 (4.69 - 13.94) | 0.07 |
| Diarrhea | 230 | 2.46 (1.50 - 4.04) | 1.9 (1.17 - 3.10) | 3.28 (2.02 - 5.33) | 2.47 (1.50 - 4.06) | 0.67 |
| Financial impact | 230 | 9.92 (5.65 - 17.43) | 6.97 (4.01 - 12.14) | 6.45 (3.72 - 11.20) | 6.42 (3.65 - 11.3) | 0.24 |
| EORTC QLQ-BR23 | ||||||
| Functioning | ||||||
| Body image | 229 | 38.50 (26.43 - 56.06) | 30.60 (21.23 - 44.12) | 41.82 (29.06 - 60.19) | 31.51 (21.69 - 45.77) | 0.62 |
| Sexual functioning | 216 | 4.15 (2.46 – 7.00) | 2.23 (1.32 - 3.76) | 4.77 (2.81 - 8.08) | 4.08 (2.40 - 6.93) | 0.55 |
| Future perspective | 229 | 18.36 (10.99 - 30.67) | 22.97 (13.94 - 37.85) | 28.15 (17.13 - 46.27) | 15.63 (9.39 - 26.03) | 0.64 |
| Symptom | ||||||
| Systematic therapy side effects | 230 | 24.90 (18.63 - 33.29) | 19.03 (14.31 - 25.32) | 18.20 (13.69 - 24.18) | 22.45 (16.78 - 30.04) | 0.65 |
| Breast symptoms | 230 | 16.03 (10.35 - 24.83) | 7.07 (4.60 - 10.87) | 8.36 (5.45 - 12.82) | 10.97 (7.07 - 17.01) | 0.35 |
| Arm symptoms | 230 | 27.23 (18.22 - 40.71) | 21.05 (14.18 - 31.25) | 20.81 (14.04 - 30.85) | 20.65 (13.8 - 30.91) | 0.32 |
| Upset by hair loss | 151 | 24.94 (12.52 - 49.66) | 29.96 (14.49 - 61.98) | 34.18 (16.69 – 70.00) | 17.16 (8.42 - 34.97) | 0.44 |
LS means least squares means, 95% CI 95% confidence interval, HRQoL health-related quality of life, EORTC QLQ- C30 European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30, BR23 breast cancer module 23
aAdjusted for age at diagnosis (year; continuous), body mass index at diagnosis (kg/m2; continuous), energy intake (kcal/d; continuous), marital status (married or cohabitation, others), education level (high school or below, college or above), physical activity (MET-hr/wk.; continuous), breast cancer stage at diagnosis (I,II,III), time since surgery (months; continuous) and menopausal status at diagnosis (premenopausal, postmenopausal status)