Table 3.
Demographic characteristics of STEMI patients and comparison between patients with and without MACE.
| All patients (n = 96) |
MACE negative (n = 86) | MACE positive (n = 10) | |
|---|---|---|---|
| Baseline characteristics | |||
| Age, years | 61.79 ± 1.33 | 61.31 ± 1.41 | 65.90 ± 4.14 |
| Male sex, % | 65.6 | 67.4 | 50 |
| White, % | 93.8 | 93 | 100 |
| Medications used at baseline | |||
| ASA, % | 27.1 | 27.9 | 20 |
| Statin, % | 31.3 | 32.6 | 20 |
| Beta blocker, % | 26 | 27.9 | 10 |
| ACEi, % | 27.1 | 26.7 | 30 |
| Diuretic, % | 6.3 | 5.8 | 10 |
| Risk factors | |||
| HTN, % | 49 | 46.5 | 70 |
| DM, % | 26 | 23.3 | 50 |
| Smoking, % | 67.7 | 67.4 | 70 |
| Prior CHF, % | 5.2 | 4.7 | 10 |
| Prior MI, % | 15.6 | 16.3 | 10 |
| Labs | |||
| HbA1c, % | 6.49 ± 0.23 | 6.32 ± 0.21 | 8.0 ± 1.18 |
| LDL, mg/dL | 114.84 ± 5.03 | 114.58 ± 5.18 | 117.29 ± 20.56 |
| BNP, pg/mL | 218.18 ± 60.96 | 178.39 ± 62.05 | 470.17 ± 198.01* |
| CK, U/L | 891.01 ± 74.68 | 863.48 ± 74.41 | 1100.20 ± 311.28 |
| CK-MB, ng/mL | 54.35 ± 5.44 | 52.81 ± 5.34 | 67.63 ± 25.97 |
| Peak troponin, ng/mL | 92.65 ± 10.77 | 86.45 ± 11.01 | 145.99 ± 39.45 |
| Serum galectin-3, ng/mL | 13.144 ± 0.920 | 11.716 ± 0.692 | 25.427 ± 5.224 * |
| Left ventricular functional parameters | |||
| LVEF post-MI, % | 49.01 ± 1.35 | 49.50 ± 1.37 | 43.88 ± 5.98 |
| LVEDP, mm Hg | 22.77 ± 0.949 | 22.37 ± 1.02 | 23.44 ± 3.45 |
| E/E′ | 9.63 ± 0.44 | 9.19 ± 0.41 | 13.07 ± 1.92* |
| LAVI, mL/m2 | 22.88 ± 0.95 | 22.85 ± 0.97 | 23.11 ± 3.65 |
| LVSI | 1.34 ± 0.04 | 1.29 ± 0.31 | 1.67 ± 0.18 |
| %FM | 73.09 ± 2.58 | 75.59 ± 2.34 | 54.50 ± 12.08 |
Abbreviations: ACEi, angiotensin converting enzyme inhibitor; ASA, aspirin; BNP, brain natriuretic peptide; CHF, congestive heart failure, CK, creatine kinase; DM, diabetes mellitus; %FM, percentage of normally functioning myocardium; HbA1c, hemoglobin A1c; HF, heart failure; HTN, hypertension; LDL, low density lipoprotein; MACE: major adverse cardiovascular event, defined as composite outcome of mortality, recurrent MI, stroke, and congestive HF hospitalization; MI, myocardial infarction; LAVI, left atrial volume index; LVEDP, left ventricular end-diastolic pressure (on ventriculogram); LVEF, left ventricular ejection fraction (on ventriculogram); LVSI, left ventricular score index; STEMI, ST-elevation myocardial infarction.
Results are expressed as percentage, or mean ± SEM.
P < .05 vs MACE negative.