Figure 2.

Collective tSNE Analysis Distinguishes Major Luminal and Myoepithelial Lineages

(A) The raw data have been transformed with arcsinh with the cofactor of 5. tSNE maps from HMECs at p4 from women <30 years old (merged and subsampled at 50,000 cells, n = 16), >30 < 50 years old (n = 13), and >50 years old (n = 15).

(B) Log₂ fold change of marker expression of LEP over MEP manually gated from tSNE projection map in HMECs from women <30 years old, >30 < 50 years old, and >50 years old. Data are log₂ of ratio of median ± SD.

(C) K19 and K14 expression in LEP as a function of age. 250MK, 90P, 245AT, 173T, and an outlier 42P were excluded from the analysis.

See also Figures S1–S3.