Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase system. Ninety percent of patients with chronic granulomatous disease carry mutations in either CYBB (gp91phox) or NCF1 (p47phox). Mutations in either the membrane or cytosolic domain lead to a disruption of respiratory burst in phagocytes.
