Table 2.
The EC50 and CC50 of Compound 3 Against each Hepatitis C Virus (HCV) Chimeric Genotype, Determined as Described in the Methods and Shown in Detail in Supplementary Figure 1
| HCV Chimeric Genotype | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| 1a | 1b | 2a | 2b | 3a | 4a | 5a | 6a | 7a | |
| EC 50 (µM) | 12.55 | 6.24 | 0.00059 | 0.0080 | 8.11 | 8.99 | 9.465 | 6.47 | 10.99 |
| CC 50 (µM) | 25.11 | 14.02 | 26.42 | 26.54 | 26.06 | 26.64 | 25.85 | 22.18 | 26.9 |
Abbreviations: EC50, 50% viral inhibition; CC50, 50% cytotoxicity.