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The expression levels of DNMT3A and TDG are decreased in DS PBMCs. Scatter plot showing median and interquartile ranges of DNMT1 (A), DNMT3A (B), DNMT3B (C), and TDG (D) levels in DS and control (C) subjects. Statistical analysis was performed by Mann–Whitney U-test for DNMT3A and unpaired t-test for TDG, *p < .05; ***p < .001.
