Fig. 2.

NCBI BLAST analysis of full length and C-terminus of TBCG_03312 protein an Mtb oxireductase sequences. In (A) red lines are TBCG_03312 (from Mtb C strain) and Mtb oxidoreductase (from MTB423 strain). Purple lines represent Mtb nitroreductase from 48 different strains of Mtb as well as other Mycobacterium species. In (B) BLAST analysis was set for Max Target Sequences of 50 and confirm that only one significant matching hit was found (oxireductase from RGTB423). Note that the E value for isoleucine-tRNA ligase from Brevibacterium sp is not significant. (C) represents a schematic illustration of the genomic distance separating the strains H37Rv, C, and MTB423. Distance in number of single nucleotide substitutions as obtained from a MUMmer comparison of the genomes (see Methods).