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Aβ level in the brains of 2×TgAD mice (A) Quantification of the number of neuritic plaques immunostained by 4G8. (B) Quantification of the number of neuritic plaques stained by thioflavin S. (C) Aβ40 level in the transgenic brain tissues. (D) Aβ42 level in the transgenic brain tissues. *P < 0.05 and **P < 0.01. ***P < 0.05 vs. 1-month-AD-sham. ****P < 0.05 vs. 1-month-AD-ovx. A two-way ANOVA and a post hoc Bonferroni adjustment were used. Data are presented as the mean ± SEM.
