Skip to main content
. 2018 Mar 29;50(5):447–455. doi: 10.1093/abbs/gmy032

Figure 6.

Figure 6.

Expression of Cath-B in the mouse brains (A) Expression of Cath-B in the CA1 of the hippocampus of mice in all groups. Upper panels represent 1 week after ovariectomy (a–d). Middle panels represent 1 month after ovariectomy (e–h). Lower panels represent 3 months after ovariectomy (i–l). Cath-B-positive puncta were observed (red puncta). (B) Quantification of Cath-B in the CA1 region of the hippocampus showed a significant decrease in the ovx model compared with that in the sham in both WT and 2×TgAD mice. (C) Expression of Cath-B in the cortex of AD mice (m–r). (D) Quantification of Cath-B in the cortex showed a significant decrease in the ovx model compared with that in the sham in both WT and 2×TgAD mice. Nuclei were stained blue with DAPI. Scale bar in picture A: 20 μm; Scale bar in picture C: 10 μm. Data are presented as the mean ± SEM. *P < 0.05, **P < 0.01, and ***P < 0.001.